Genetic Conditions currently monitored by the Red Angus Society of Australia are

Osteopetrosis (OS) - Calves are born prematurely (10-30 days premature). Typically calves are born dead, but if born alive will die within 24 hours after birth. Calves possess a short lower jaw and impacted molars. Long bones are fragile and can be broken with ease.

Alpha Mannosidosis (MA) – Alpha Mannosidosis is an inherited and lethal lyosomal storage of Angus cattle. Affected calves are born alive and may display no physical deformities. Prior to reaching sexual maturity affected animals show severe, progressive neurological disease characterized by tremors’ of the head, loss of muscle coordination, and aggression when handled. The net effect is eventual death.

Arthogryposis Multiplex (AM) - The spine is bent and twisted in affected calves. The calves are small and appear thin due to limited muscle development. Legs are often rigid and may be hyper extended (common in rear limbs) or contracted. In some cases the rigid limbs result in calving difficulties. Additional unique features are recognized during laboratory examination.

Neuropathic Hydrocephalus (NH) -The calves are born near term and have low birth weights. The cranium is markedly enlarged (volleyball to basketball sized). The bones of the skull are malformed and appear as loosely organized bony plates that fall apart when the cavity is opened. The cranial cavity is filled with fluid and no recognizable brain tissue is evident. The spinal canal is also dilated and no observable spinal tissue is found.

The Genetic Status for each animal is indicated by the Genetic Condition abbreviation and then the status of the animal eg Osteopetrosis tested free - OSF

 

Code Explanation (First two characters indicate Genetic Condition)

_ _F

Indicates that the sample submitted for this animal has been tested and found to be free of the causative mutation responsible for the indicated Genetic Condition. This animal is homozygous free, meaning that it has two copies of the normal variant (or allele) of the gene.

_ _C

Indicates that the sample submitted for this animal has been tested and found to be a carrier of the causative mutation responsible for the indicated Genetic Condition.This animal is heterozygous for the mutation, meaning that it has one mutant allele and one normal allele. This animal could pass the mutation to approximately half of its progeny.

_ _ __%

Indicates that, based on pedigree information supplied by the breeder of the animal, the animal has a chance to be a carrier of the mutation responsible for the indicated Genetic Condition but has not been tested. The higher the indicated percentage, the larger the chance the animal may be a carrier. Breeders are recommended to test this animal for the Genetic Condition prior to using this animal in a breeding program.

_ _FU

Indicates that, based on pedigree information supplied by the breeder of the animal, the animal is expected to be free of the mutation responsible for the indicated Genetic Condition but has not been tested. However, this animal has not been tested for the causative mutation and the Red Angus Society of Australia inc gives no guarantee as to the animal's "free" status.

_ _MA

Although affected calves will be dead at birth and are rarely tested, they would be homozygous for the mutation responsible for the indicated Genetic Condition and have two copies of the mutant variant of the gene.


Disclaimer: Genetic test results are based on samples provided by breeders. The Red Angus Society of Australia Inc makes no guarantee or warranty about the accuracy or completeness of, any information relating to the status of a particular animal; and, disclaims all responsibility for information and all liability (including without limitation, liability in negligence) for all expenses, losses, damages, and costs you may incur as a result of information being inaccurate or incomplete in any way for any reason.